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Department
of Statistics |
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David M. Zucker
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Department
of Statistics |
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Last revised: 20 |February 2012
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Born 1961, Baltimore, Maryland, USA.
Moved to Jerusalem, Israel, in September 1992.
One of the best decisions in my life.
Married to Janis Zucker, with six children:
Yossi, Avi, Naomi, Shlomo, Peninah, and Miriam
(all of whom are very nice, if I may say so myself).
Family Picture
Education
JD, 1987, University of Maryland at Baltimore
PhD, 1986, Johns Hopkins University, Mathematical Sciences
(concentration in probability and statistics)
MA, 1981, Johns Hopkins University, Mathematical Sciences
BA, 1980, Johns Hopkins University, Mathematical Sciences
Professional Employment Background
1992-Present Faculty Member
Senior Lecturer - October 1992 to March 2002
Associate Professor - March 2002 to December 2007
Professor - December 2007 to present
Department of Statistics
Hebrew University of Jerusalem
1986-1992 Mathematical Statistician
Biostatistics Research Branch
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH), USA
1983-1986 Mathematical Statistician
Statistical Evaluation and Research Branch (SERB)
Center for Drugs and Biologics (CDER)
Food and Drug Adminstration (FDA), USA
At the FDA, I was a statistical reviewer of clinical trials submitted in New Drug Applications (NDA's) by drug companies to obtain new drug approvals. At the NIH, I worked mainly on design of large scale NIH-run clinical trials, mostly in the cardiovascular area. I also engaged in various other statistical consulting activities with NIH researchers and in biostatistical methodology research. At the Hebrew University, I have been teaching general statistics and biostatistics courses (at the BA and MA levels) and have been engaged in statistical methods research. I have been the coordinator of the Statistics Departments MA track in biostatistics. Click here to access a Hebrew document describing this program.
In addition to the foregoing full time positions, I have engaged in part-time statistical consulting over the years for a variety of clients, including Hebrew University researchers (especially in the School of Public Health), Teva Pharmaceuticals, Agis Pharmaceuticals, Keryx Biopharmaceuticals, and Neurotrax, Inc.
Research Interests
Survival Analysis
Nonlinear Statistical Models with Covariate Measurement Error
Analysis of Repeated Measurement Data (Continuous and Binary)
Clinical Trial Design, including interim sample size updating
Higher Order Asymptotics
Editorial Service
Co-Editor, Biometrics, 2008-2010 (one of three chief editors)
Associate Editor, Biometrics, 2003-07
Associate Editor, Controlled Clinical Trials, 1998-99
Referee for a variety of statistical and biomedical research journals
Inference for the Proportional Hazards Model with Misclassified Discrete-Valued Covariates, with D. Spiegelman, Biometrics 60:324-334 (June 2004).
In referencing this paper, please cite the published version.
Fortran software for the method:
Documentation
Basic program: (1) Driver, (2) Subroutines
Extended program to cover left truncation: (1) Driver, (2) Subroutines
A pseudo partial likelihood method
for semi-parametric survival regression with covariate
errors.
In referencing this paper,
please cite the published version.
Journal of the American
Statistical Association 100:1264-1277 (December 2005).
A
regularization corrected score method for nonlinear
regression models with covariate error, with M. Gorfine, Y.
Li, M. G. Tadesse, and D. Spiegelman (to appear in Biometrics).
Manuscript
R
Code for Univariate Simulations
R
Code for Multivariate Simulations
R
Code for Example
Testing for a
changepoint in the Cox survival regression model, with Sarit
Agami and Donna Spiegelman (submitted for publication).
Manuscript
Code
Selected Statistical/Scientific
Publications
Tian, L, Zucker, DM, and Wei, LJ. (2005). On the Cox model with time-varying regression coefficients. Journal of the American Statistical Association 100:172-183.
Zucker, DM. (2005). A pseudo partial likelihood method for semi-parametric survival regression with covariate errors. Journal of the American Statistical Association 100:1264-1277.
Rosen, L, Manor, O, Engelhard, D, Zucker, D. (2006). In defense of the randomized controlled trial for health promotion research. American Journal of Public Health 96:1181-1186.
Gorfine M, Zucker DM. and Hsu L. (2006). Prospective survival analysis with a general semiparametric shared frailty model: a pseudo full likelihood approach. Biometrika 93:735-741.
Rosen LR, Manor O, Englehard D, Zucker D. (2006). Design of the Jerusalem Handwashing Study: meeting the challenges of a preschool-based public health intervention trial. Clinical Trials 3:376-384.
Zucker DM, Gorfine M, Hsu L. (2008). Pseudo full likelihood estimation for prospective survival analysis with a general semiparametric shared frailty model: asymptotic theory. Journal of Statistical Planning and Inference 138:1998-2016
Zucker DM, and Spiegelman, D. (2008). Corrected score estimation in the proportional hazards model with misclassified discrete covariates. Statistics in Medicine 27:1911-1933. Previous technical report version covering the case of general relative risk functions.
Gorfine M, Zucker DM, Hsu L. (2009). Case-control survival analysis with a general semiparametric shared frailty model: a pseudo full likelihood approach. Annals of Statistics 37:1489-1517.
Rosen LJ, Manor O, Brody D, Englehard D, Shtarkshall R, Zucker D (2009). From pills to programs: lessons from medicine for developing effective lifestyle interventions. Preventive Medicine 49:12-18.
Chen YH, and Zucker
DM (2009). Case-cohort analysis with semiparametric
transformation models. Journal
of
Statistical Planning and Inference 39:3706-3717.
Liao X, Zucker DM, Li
Y, and Spiegelman D. (2011). Survival analysis with error-prone
time-varying covariates: a risk set calibration approach. Biometrics 67:50–58.
Martinussen T, Scheike T, and Zucker DM. (2011). The Aalen
additive gamma frailty hazards model. Biometrika, to appear.
Complete
publications list: click here
(last updated February 2012)
Sample Size
Redetermination for Repeated Measures Studies (see Zucker and
Denne, 2002, Biometrics)
Software
for
inflation factor - Nonparametric Approach A
Software
for
Nonparametric Approach B (basic method + inflation factor)
Software
for
Parametric Approach C (Weibull) (basic method + inflation
factor)
Remark
on
inflation factor
Inference for a family of survival models encompassing the proportional hazards and proportional odds models
(see Zucker and Yang, 2006, Statistics in Medicine)
Fortran software for the method:
Basic program: (1) Driver, (2) Subroutines
Corrected score estimation in the proportional hazards model with misclassified discrete covariates
(see Zucker and Spiegelman, 2008, Statistics in Medicine)
Fortran software for the method:
Documentation
Code
Sample Driver File
Executable File for Running on PC
Other Downloads
Notes on Hierarchical Models
Courses Taught (selected list)
Introductory Statistics for Economics Majors B (1st year BA)
Nonparametric Statistics for Nonstatisticians
Statistical Inference and Its Applications A (2nd year BA)
Statistical Inference and Its Applications B (2nd year BA)
Regression and Linear Models (2nd year BA)
Sampling Theory (2nd year BA)
Statistical Models and Their Applications (3rd year BA)
Principles of Research Design and Sampling Theory (2nd/3rd year BA and MA)
Survival Analysis (3rd year BA and MA)
Binary Data Analysis (3rd year BA and MA)
Topics in Biostatistics (3rd year BA and MA)
Measurement Error Models (3rd year BA and MA)
Advanced SAS Applications (3rd year BA and MA)
Repeated Measures Analysis (MA)
Matrix Theory With Statistical Applications (MA)
Asymptotic Statistical Theory (MA and PhD)
Eastern Mediterranean Region of the
International Biometric Society (EMR-IBS)
In 2001, the Eastern
Mediterranean Region of the International Biometric
Society (EMR-IBS) was founded to foster interaction
among biostatisticians in the Eastern Mediterranean
Region. I have served the EMR in various capacities over
the years. In particular, I was, along with Orly Manor,
one of the lead co-organizers of the Fourth Meeting of
the EMR-IBS, held at the Hilton Hotel, Eilat, Israel, on
January 23-25, 2007. I am glad to say that this
conference was very successful. I also served as
President of the EMR from May 2007 to May 2009. Link to EMR-IBS regional
website
Zucker, D. M. (2004, 2007) (English translation). Voice of Weepers: Commentary of the Dubner Maggid on the Book of Lamentations. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2005) (English translation). Voice of Rejoicing and Salvation: Commentary of the Dubner Maggid on the Book of Esther. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2006) (English translation). Voice of the Dove: Commentary of the Dubner Maggid on the Book of Ruth and Chapter 19 of Exodus. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2008) (English translation). A Voice Shall Sing Forth: Commentary of the Dubner Maggid on the Song of Songs. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2009) (English translation). Voice of Nobles: Commentary of the Dubner Maggid on the Book of Ecclesiastes. Feldheim Publishers, Monsey NY and Jerusalem.
The above works were originally published in Hebrew in 1819 posthumously by Rabbi Jacob Kranz, the Maggid of Dubno, under the titles Kol Bochim, Kol Rinah V’Yeshuah, Kol HaTor, Kol Yeshorer, and Kol Negidim, respectively, in a volume called Kol Yaakov containing commentaries on the Five Scrolls. The material was arranged and edited under the direction of Rabbi Kranz’s son Isaac. (In Voice of the Dove, the material on Exodus comes from Ohel Yaacov, the Maggid’s commentary on the Chumash [Five Books of Moses], as compiled by Rav Avraham Dov Beirush Flamm.)
For more information on these works, see www.jlm-dubno-maggid.org.
